| Variable | % missing | SwedeHF | % missing | SwedeHF | Case NPR | Control SwedeHF | Control NPR |
|---|---|---|---|---|---|---|---|
| n | 131296 | 243213 | 423092 | 388841 | 782402 | ||
| ncontrols | 0.0 | 2.0 [1.0, 2.0] | 0.0 | 2.0 [2.0, 2.0] | 2.0 [2.0, 2.0] | 0.0 [0.0, 0.0] | 0.0 [0.0, 0.0] |
| Time in hospital at index hospitalization (days)1 | 64.7 | 5.0 [3.0, 9.0] | 68.2 | 5.0 [3.0, 9.0] | |||
| Index year1 | 0.0 | 2016.0 [2011.0, 2021.0] | 0.0 | 2016.0 [2011.0, 2020.0] | 2011.0 [2005.0, 2016.0] | 2014.0 [2010.0, 2018.0] | 2010.0 [2005.0, 2016.0] |
| Type of visit Index1 | 0.0 | 76002 (57.9) | 0.0 | 132567 (54.5) | |||
| LVEF (%)1 | 82.0 | 40.0 [30.0, 50.0] | 82.4 | 40.0 [30.0, 45.0] | |||
| LVEF (%)1 | 21.0 | 18.6 | |||||
| ≥50 | 27080 (26.1) | 44258 (22.4) | |||||
| 40-49 | 25940 (25.0) | 47953 (24.2) | |||||
| 30-39 | 26777 (25.8) | 53900 (27.2) | |||||
| <30 | 23906 (23.1) | 51853 (26.2) | |||||
| LVEF (%)1 | 21.0 | 18.6 | |||||
| HFrEF | 50683 (48.9) | 105753 (53.4) | |||||
| HFmrEF | 25940 (25.0) | 47953 (24.2) | |||||
| HFpEF | 27080 (26.1) | 44258 (22.4) | |||||
| Sex Male1 | 0.0 | 81474 (62.1) | 0.0 | 156846 (64.5) | 226530 (53.5) | 244108 (62.8) | 409105 (52.3) |
| Age (years)1 | 0.0 | 77.0 [69.0, 84.0] | 0.0 | 76.0 [67.0, 82.0] | 80.0 [71.0, 87.0] | 75.0 [67.0, 82.0] | 79.0 [70.0, 86.0] |
| Civil status Single1 | 27.5 | 42011 (44.1) | 27.0 | 73713 (41.5) | |||
| Living conditions Own home1 | 41.7 | 72630 (94.9) | 41.2 | 137784 (96.3) | |||
| Location In-patient1 | 0.0 | 46307 (35.3) | 0.0 | 77457 (31.8) | |||
| Smoking1 | 27.2 | 23.9 | |||||
| Current | 10233 (10.7) | 19722 (10.7) | |||||
| Former | 41979 (43.9) | 83063 (44.9) | |||||
| Never | 43349 (45.4) | 82202 (44.4) | |||||
| Smoking1 | 27.2 | 10233 (10.7) | 23.9 | 19722 (10.7) | |||
| Alcohol Risk1 | 41.4 | 3381 (4.4) | 37.8 | 6402 (4.2) | |||
| Duration of HF (months) ≥61 | 2.7 | 78710 (61.6) | 2.5 | 146331 (61.7) | |||
| Primary etiology1 | 39.2 | 38.4 | |||||
| DCM | 5171 (6.5) | 12041 (8.0) | |||||
| Heart valve disease | 6248 (7.8) | 10910 (7.3) | |||||
| Hypertension | 20746 (26.0) | 37413 (25.0) | |||||
| IHD | 30194 (37.8) | 58995 (39.4) | |||||
| Known alcoholic cardiomyopathy | 532 (0.7) | 1066 (0.7) | |||||
| Other | 16923 (21.2) | 29290 (19.6) | |||||
| NYHA class1 | 28.6 | 24.6 | |||||
| I | 13051 (13.9) | 23403 (12.8) | |||||
| II | 43789 (46.7) | 89091 (48.6) | |||||
| III | 33426 (35.6) | 65573 (35.7) | |||||
| IV | 3514 (3.7) | 5375 (2.9) | |||||
| NYHA class III-IV1 | 28.6 | 36940 (39.4) | 24.6 | 70948 (38.7) | |||
| Killip class1 | 94.0 | 95.5 | |||||
| Chock or hypertension | 19 (0.2) | 41 (0.4) | |||||
| Edema | 209 (2.7) | 285 (2.6) | |||||
| No signs of HF | 3678 (46.7) | 5348 (48.6) | |||||
| Rales or crackles | 3974 (50.4) | 5338 (48.5) | |||||
| Weight (kg)1 | 14.5 | 77.6 [66.2, 90.0] | 13.3 | 79.0 [68.0, 92.0] | |||
| Weight at admission/visit (kg)1 | 31.8 | 78.0 [66.8, 90.8] | 35.0 | 79.5 [68.0, 92.0] | |||
| Weight at discharge (hospitalized patients) (kg)1 | 94.4 | 75.4 [63.9, 88.5] | 95.8 | 77.0 [65.2, 90.2] | |||
| Height (cm)1 | 29.6 | 172.0 [165.0, 179.0] | 24.2 | 173.0 [165.0, 180.0] | |||
| Systolic blood pressure (mmHg)1 | 4.5 | 125.0 [110.0, 140.0] | 3.9 | 125.0 [110.0, 140.0] | |||
| Systolic blood pressure at admission/visit (mmHg)1 | 22.8 | 125.0 [111.0, 140.0] | 26.9 | 125.0 [111.0, 140.0] | |||
| Systolic blood pressure at discharge (hospitalized patients) (mmHg)1 | 93.5 | 125.0 [111.0, 140.0] | 95.2 | 124.0 [110.0, 140.0] | |||
| Diastolic blood pressure (mmHg)1 | 4.4 | 70.0 [65.0, 80.0] | 3.8 | 70.0 [65.0, 80.0] | |||
| Diastolic blood pressure at admission/visit (mmHg)1 | 22.7 | 72.0 [65.0, 80.0] | 26.8 | 72.0 [65.0, 80.0] | |||
| Diastolic blood pressure at discharge (hospitalized patients) (mmHg)1 | 93.5 | 72.0 [65.0, 80.0] | 95.2 | 72.0 [65.0, 80.0] | |||
| Mean arterial pressure (mmHg)1 | 4.4 | 90.0 [81.7, 99.3] | 3.8 | 90.0 [81.7, 98.7] | |||
| Mean arterial pressure (mmHg) >901 | 4.4 | 59534 (47.4) | 3.8 | 110609 (47.3) | |||
| Heart rate (beats/min)1 | 7.0 | 71.0 [62.0, 82.0] | 6.2 | 70.0 [62.0, 81.0] | |||
| Heart rate at admission/visit (beats/min)1 | 24.6 | 71.0 [63.0, 83.0] | 28.6 | 71.0 [62.0, 82.0] | |||
| Heart rate at discharge (hospitalized patients) (beats/min)1 | 93.8 | 74.0 [65.0, 85.0] | 95.3 | 74.0 [65.0, 85.0] | |||
| Heart rate (beats/min) >701 | 7.0 | 62063 (50.8) | 6.2 | 113881 (49.9) | |||
| Hemoglobin (g/L)1 | 9.5 | 132.0 [119.0, 144.0] | 9.5 | 133.0 [120.0, 145.0] | |||
| Hemoglobin at admission/visit (g/L)1 | 27.7 | 132.0 [119.0, 145.0] | 32.1 | 134.0 [121.0, 146.0] | |||
| Hemoglobin at discharge (hospitalized patients) (g/L)1 | 95.9 | 119.0 [106.0, 135.0] | 96.9 | 122.0 [108.0, 137.0] | |||
| Anemia1 | 9.5 | 43147 (36.3) | 9.4 | 74508 (33.8) | |||
| Potassium (mmol/L)1 | 18.3 | 4.2 [3.9, 4.5] | 16.9 | 4.2 [3.9, 4.5] | |||
| Potassium at admission/visit (mmol/L)1 | 32.2 | 4.2 [3.9, 4.5] | 35.0 | 4.2 [4.0, 4.5] | |||
| Potassium at discharge (hospitalized patients) (mmol/L)1 | 94.3 | 4.0 [3.7, 4.3] | 95.7 | 4.0 [3.7, 4.3] | |||
| Potassium (mmol/L)1 | 18.3 | 16.9 | |||||
| 3.5-5 (Normakalemia) | 98417 (91.8) | 187190 (92.6) | |||||
| <3.5 (Hypokalemia) | 4537 (4.2) | 7279 (3.6) | |||||
| >5 (Hyperkalemia) | 4285 (4.0) | 7614 (3.8) | |||||
| Sodium (mmol/L)1 | 31.4 | 140.0 [138.0, 142.0] | 31.1 | 140.0 [138.0, 142.0] | |||
| Sodium at admission/visit (mmol/L)1 | 41.7 | 140.0 [138.0, 142.0] | 44.2 | 140.0 [138.0, 142.0] | |||
| Sodium at discharge (hospitalized patients) (mmol/L)1 | 94.5 | 140.0 [138.0, 142.0] | 95.9 | 140.0 [138.0, 142.0] | |||
| Creatinine (µmol/L)1 | 3.8 | 97.0 [79.0, 125.0] | 3.5 | 96.0 [79.0, 122.0] | |||
| Creatinine at admission/visit (µmol/L)1 | 22.3 | 95.0 [78.0, 121.0] | 26.6 | 94.0 [77.0, 118.0] | |||
| Creatinine at discharge (hospitalized patients) (µmol/L)1 | 94.3 | 99.0 [78.0, 133.0] | 95.7 | 97.0 [78.0, 127.0] | |||
| eGFR (mL/min/1.73 m²)1 | 3.5 | 63.0 [45.3, 82.8] | 3.2 | 64.8 [47.2, 84.0] | |||
| eGFR (mL/min/1.73 m²) <601 | 3.5 | 57761 (45.6) | 3.2 | 101326 (43.0) | |||
| NT-proBNP (pg/mL)1 | 41.0 | 1908.0 [724.0, 4602.0] | 40.2 | 1812.0 [716.0, 4196.0] | |||
| NT-proBNP at admission/visit (pg/mL)1 | 50.1 | 1810.0 [682.0, 4315.0] | 51.7 | 1709.0 [669.0, 3921.0] | |||
| NT-proBNP at discharge (hospitalized patients) (pg/mL)1 | 97.7 | 3681.5 [1653.8, 8593.2] | 98.2 | 3388.0 [1530.0, 7540.0] | |||
| BNP (pg/mL)1 | 96.2 | 586.0 [224.0, 1352.5] | 95.8 | 529.0 [203.0, 1242.0] | |||
| Transferrin saturation (%)1 | 84.8 | 24.0 [17.0, 33.0] | 85.4 | 25.0 [17.0, 33.0] | |||
| Ferritin (µg/L)1 | 82.7 | 143.0 [71.0, 269.0] | 83.4 | 143.0 [71.0, 265.0] | |||
| QRS width (ms)1 | 22.2 | 104.0 [91.0, 134.0] | 22.2 | 106.0 [92.0, 136.0] | |||
| Left Bundle Branch Block (LBBB)1 | 22.8 | 17584 (17.3) | 23.0 | 34788 (18.6) | |||
| Loop diuretic IV1 | 77.8 | 6826 (23.4) | 78.0 | 9640 (18.0) | |||
| Ferric carboxymaltose IV1 | 49.6 | 3705 (5.6) | 50.8 | 6233 (5.2) | |||
| Ferric carboxymaltose IV dose (mg)1 | 97.3 | 1000.0 [1000.0, 1000.0] | 97.6 | 1000.0 [1000.0, 1000.0] | |||
| Unplanned inotrope support1 | 46.4 | 1416 (2.0) | 48.0 | 3772 (3.0) | |||
| Diuretic1 | 0.6 | 97144 (74.4) | 0.5 | 180927 (74.7) | |||
| Loop diuretic1 | 23.7 | 70551 (70.5) | 23.7 | 130817 (70.5) | |||
| Loop diuretic substance1 | 68.5 | 70.2 | |||||
| Bumetanid | 278 (0.7) | 422 (0.6) | |||||
| Furosemid | 40902 (98.9) | 71806 (99.0) | |||||
| Toresamid | 182 (0.4) | 306 (0.4) | |||||
| Loop diuretic dose (mg/24h)1 | 56.3 | 40.0 [40.0, 80.0] | 56.1 | 40.0 [40.0, 80.0] | |||
| Loop diuretic usage When necessary1 | 46.4 | 15887 (22.6) | 46.3 | 29789 (22.8) | |||
| ACEi1 | 0.5 | 59533 (45.6) | 0.4 | 115746 (47.8) | |||
| ACEi dose (mg/24h)1 | 54.7 | 10.0 [5.0, 15.0] | 52.5 | 10.0 [5.0, 15.0] | |||
| ARB1 | 1.0 | 36376 (28.0) | 0.8 | 71105 (29.5) | |||
| ARB dose (mg/24h)1 | 72.3 | 32.0 [12.5, 50.0] | 70.8 | 32.0 [12.5, 50.0] | |||
| ARNi1 | 48.4 | 11531 (17.0) | 49.8 | 21431 (17.5) | |||
| ACEi/ARB/ARNi1 | 1.1 | 105685 (81.4) | 0.9 | 204591 (84.9) | |||
| Beta-blocker1 | 0.5 | 112821 (86.3) | 0.3 | 213270 (88.0) | |||
| Beta-blocker dose (mg/24h)1 | 14.3 | 25.0 [5.0, 100.0] | 12.5 | 25.0 [5.0, 100.0] | |||
| MRA1 | 0.8 | 52972 (40.7) | 0.6 | 100969 (41.8) | |||
| MRA dose (mg/24h)1 | 70.4 | 25.0 [25.0, 25.0] | 70.3 | 25.0 [25.0, 25.0] | |||
| Digoxin1 | 0.5 | 15924 (12.2) | 0.4 | 29920 (12.4) | |||
| Platelet inhibitor1 | 0.6 | 48691 (37.3) | 0.4 | 90156 (37.2) | |||
| Oral anticoagulant1 | 0.5 | 62570 (47.9) | 0.4 | 119716 (49.4) | |||
| Statin1 | 0.5 | 62239 (47.6) | 0.4 | 121678 (50.2) | |||
| Nitrate1 | 0.6 | 15941 (12.2) | 0.5 | 28684 (11.8) | |||
| SGLT2i1 | 76.5 | 16712 (54.2) | 80.7 | 24348 (52.0) | |||
| SGLT2i dose (mg/24h)1 | 87.3 | 10.0 [10.0, 10.0] | 90.0 | 10.0 [10.0, 10.0] | |||
| Sinus node inhibitor1 | 50.4 | 296 (0.5) | 52.1 | 607 (0.5) | |||
| Device therapy1 | 1.2 | 1.5 | |||||
| No | 107045 (82.5) | 193346 (80.7) | |||||
| Pacemaker | 12046 (9.3) | 21990 (9.2) | |||||
| CRT-P | 2493 (1.9) | 5248 (2.2) | |||||
| CRT-D | 3944 (3.0) | 9419 (3.9) | |||||
| ICD | 4163 (3.2) | 9539 (4.0) | |||||
| Device therapy CRT/ICD1 | 1.2 | 10600 (8.2) | 1.5 | 24206 (10.1) | |||
| Chest X-ray1 | 39.9 | 38.6 | |||||
| No | 23182 (29.4) | 46008 (30.8) | |||||
| Normal | 18844 (23.9) | 35260 (23.6) | |||||
| Pulmonary congestion | 10169 (12.9) | 17553 (11.7) | |||||
| Cardiomegaly | 12278 (15.6) | 24341 (16.3) | |||||
| Pulmonary congestion & cardiomegaly | 14372 (18.2) | 26263 (17.6) | |||||
| Diabetes1 | 9.0 | 21793 (18.2) | 8.4 | 42621 (19.1) | |||
| Diabetes1 | 25.0 | 24.5 | |||||
| No | 78747 (79.9) | 145792 (79.4) | |||||
| Type I | 1498 (1.5) | 2670 (1.5) | |||||
| Type II | 18292 (18.6) | 35065 (19.1) | |||||
| Hypertension1 | 2.2 | 74390 (57.9) | 2.0 | 135513 (56.9) | |||
| Atrial fibrillation/flutter1 | 0.6 | 68053 (52.2) | 0.6 | 124178 (51.3) | |||
| Lung disease1 | 2.0 | 22546 (17.5) | 1.9 | 40401 (16.9) | |||
| Valve disease1 | 3.2 | 25076 (19.7) | 3.2 | 46211 (19.6) | |||
| Dilated cardiomyopathy1 | 4.3 | 12438 (9.9) | 4.4 | 28668 (12.3) | |||
| Revascularization1 | 2.8 | 33915 (26.6) | 3.0 | 67232 (28.5) | |||
| Valve surgery1 | 1.9 | 8571 (6.7) | 2.1 | 16526 (6.9) | |||
| ECG rythm1 | 8.5 | 8.1 | |||||
| Sinus | 61073 (50.8) | 114461 (51.2) | |||||
| Atrial fibrillation | 44721 (37.2) | 80484 (36.0) | |||||
| PM/Other | 14360 (12.0) | 28469 (12.7) | |||||
| Follow-up referral HF nurse clinic1 | 9.6 | 67597 (56.9) | 6.8 | 149167 (65.8) | |||
| Follow-up referral speciality1 | 7.6 | 5.3 | |||||
| Hospital | 73801 (60.8) | 151600 (65.9) | |||||
| Primary care | 42527 (35.1) | 70952 (30.8) | |||||
| Other | 4977 (4.1) | 7653 (3.3) | |||||
| Follow-up referral speciality Hospital1 | 7.6 | 73801 (60.8) | 5.3 | 151600 (65.9) | |||
| EQ5D-vas1 | 66.6 | 70.0 [50.0, 80.0] | 65.1 | 70.0 [50.0, 80.0] | |||
| EQ5D-vas1 | 66.6 | 65.1 | |||||
| 0-25 | 1999 (4.6) | 3631 (4.3) | |||||
| 26-50 | 10864 (24.8) | 20410 (24.1) | |||||
| 51-75 | 17693 (40.4) | 34748 (41.0) | |||||
| 76-100 | 13252 (30.3) | 25973 (30.6) | |||||
| Fatigue1 | 57.3 | 55.4 | |||||
| At rest | 3347 (6.0) | 5665 (5.2) | |||||
| At moderate effort | 14974 (26.7) | 27922 (25.8) | |||||
| At more than moderate effort | 28031 (50.0) | 56514 (52.2) | |||||
| Unaffected | 9759 (17.4) | 18264 (16.9) | |||||
| Out of breath1 | 56.8 | 55.0 | |||||
| At rest | 1778 (3.1) | 2831 (2.6) | |||||
| At moderate effort | 16415 (28.9) | 30715 (28.1) | |||||
| At more than moderate effort | 29374 (51.8) | 59144 (54.0) | |||||
| Unaffected | 9171 (16.2) | 16765 (15.3) | |||||
| Mobilty1 | 56.7 | 55.0 | |||||
| Bedridden | 652 (1.1) | 929 (0.8) | |||||
| Some problem | 25214 (44.3) | 45942 (42.0) | |||||
| No problem | 31019 (54.5) | 62555 (57.2) | |||||
| Hygiene1 | 57.1 | 55.4 | |||||
| Can't wash and clothe | 1070 (1.9) | 1494 (1.4) | |||||
| Some problem | 6341 (11.3) | 10305 (9.5) | |||||
| No problem | 48869 (86.8) | 96721 (89.1) | |||||
| Main activities1 | 57.3 | 55.6 | |||||
| Can't do | 2770 (4.9) | 4434 (4.1) | |||||
| Some problem | 14801 (26.4) | 27180 (25.2) | |||||
| No problem | 38437 (68.6) | 76394 (70.7) | |||||
| Pain1 | 59.1 | 57.2 | |||||
| Severe | 3420 (6.4) | 6100 (5.9) | |||||
| Moderate | 24197 (45.1) | 46814 (45.0) | |||||
| None | 26063 (48.6) | 51192 (49.2) | |||||
| Anxiety/Depression1 | 60.8 | 58.9 | |||||
| Severe | 2196 (4.3) | 3910 (3.9) | |||||
| Moderate | 18783 (36.4) | 36213 (36.2) | |||||
| None | 30553 (59.3) | 59869 (59.9) | |||||
| BMI (kg/m²)1 | 37.6 | 26.3 [23.3, 30.2] | 32.2 | 26.7 [23.6, 30.5] | |||
| BMI (kg/m²) ≥301 | 37.6 | 21533 (26.3) | 32.2 | 46197 (28.0) | |||
| Age (years)1 | 0.0 | 0.0 | |||||
| <70 | 35535 (27.1) | 74944 (30.8) | 92641 (21.9) | 125513 (32.3) | 182923 (23.4) | ||
| 70-80 | 45907 (35.0) | 89695 (36.9) | 126149 (29.8) | 148749 (38.3) | 247192 (31.6) | ||
| >80 | 49854 (38.0) | 78574 (32.3) | 204302 (48.3) | 114579 (29.5) | 352287 (45.0) | ||
| Previous HFH < 1 year12 | 0.0 | 71533 (54.5) | 0.0 | 125975 (51.8) | 287418 (67.9) | 0 (0.0) | 0 (0.0) |
| Atrial fibrillation/flutter12 | 0.0 | 77385 (58.9) | 0.0 | 140804 (57.9) | 186715 (44.1) | 26067 (6.7) | 51643 (6.6) |
| IHD12 | 0.0 | 69045 (52.6) | 0.0 | 129462 (53.2) | 191822 (45.3) | 50546 (13.0) | 105663 (13.5) |
| Hypertension12 | 0.0 | 89864 (68.4) | 0.0 | 163366 (67.2) | 218334 (51.6) | 83462 (21.5) | 148198 (18.9) |
| Diabetes12 | 0.0 | 35817 (27.3) | 0.0 | 66979 (27.5) | 96547 (22.8) | 31970 (8.2) | 57760 (7.4) |
| Valve disease12 | 0.0 | 34649 (26.4) | 0.0 | 63760 (26.2) | 64209 (15.2) | 7756 (2.0) | 13744 (1.8) |
| Country of birth3 | 0.0 | 0.0 | |||||
| Sweden | 112782 (85.9) | 207034 (85.1) | 370470 (87.6) | 338661 (87.1) | 696077 (89.0) | ||
| Europe | 14219 (10.8) | 27671 (11.4) | 42128 (10.0) | 37015 (9.5) | 66678 (8.5) | ||
| Other | 4292 (3.3) | 8503 (3.5) | 10483 (2.5) | 13134 (3.4) | 19597 (2.5) | ||
| Children3 | 0.0 | 109929 (83.7) | 0.0 | 203482 (83.7) | 350591 (82.9) | 329159 (84.7) | 655083 (83.7) |
| Marital status Single/widowed/divorced3 | 0.1 | 71010 (54.1) | 0.1 | 126939 (52.2) | 246572 (58.4) | 183021 (47.1) | 415640 (53.2) |
| Family situation Living alone3 | 0.1 | 65880 (50.2) | 0.1 | 116595 (48.0) | 232400 (55.0) | 168465 (43.4) | 391440 (50.1) |
| Education3 | 2.0 | 1.9 | |||||
| Compulsory school | 54780 (42.6) | 98733 (41.4) | 206723 (51.1) | 145478 (38.1) | 345737 (46.0) | ||
| Secondary school | 50807 (39.5) | 96407 (40.4) | 140379 (34.7) | 147188 (38.5) | 263230 (35.0) | ||
| University | 23039 (17.9) | 43351 (18.2) | 57768 (14.3) | 89225 (23.4) | 142250 (18.9) | ||
| Disposable income (100 SEK)3 | 0.1 | 1607.0 [1266.0, 2193.0] | 0.1 | 1620.0 [1276.0, 2236.0] | 1370.0 [1058.0, 1790.0] | 1659.0 [1273.0, 2484.0] | 1411.0 [1063.0, 1969.0] |
| Duration of HF (days)2 | 0.0 | 307.0 [17.0, 1734.0] | 0.0 | 336.0 [20.0, 1866.0] | 0.0 [0.0, 101.0] | ||
| Time since last HF hospitalization (days)2 | 43.0 | 25.0 [0.0, 312.0] | 42.9 | 29.0 [0.0, 352.0] | 0.0 [0.0, 0.0] | ||
| Location2 | 0.0 | 0.0 | |||||
| HF in-patient | 30437 (23.2) | 52980 (21.8) | 287418 (67.9) | ||||
| Other in-patient | 17026 (13.0) | 26259 (10.8) | 13888 (3.3) | ||||
| Out-patient | 83833 (63.9) | 163974 (67.4) | 121786 (28.8) | ||||
| Hypertension2 | 0.0 | 78237 (59.6) | 0.0 | 140966 (58.0) | 218334 (51.6) | 83462 (21.5) | 148198 (18.9) |
| Diabetes2 | 0.0 | 34289 (26.1) | 0.0 | 63765 (26.2) | 96547 (22.8) | 31970 (8.2) | 57760 (7.4) |
| Ischemic heart disease2 | 0.0 | 67708 (51.6) | 0.0 | 126796 (52.1) | 190206 (45.0) | 50213 (12.9) | 105225 (13.4) |
| Myocardial infarction2 | 0.0 | 49397 (37.6) | 0.0 | 92697 (38.1) | 130322 (30.8) | 27023 (6.9) | 54342 (6.9) |
| Angina pectoris2 | 0.0 | 23770 (18.1) | 0.0 | 45290 (18.6) | 77064 (18.2) | 15462 (4.0) | 35090 (4.5) |
| PCI2 | 0.0 | 25772 (19.6) | 0.0 | 50287 (20.7) | 47533 (11.2) | 16449 (4.2) | 23714 (3.0) |
| CABG2 | 0.0 | 33232 (25.3) | 0.0 | 65348 (26.9) | 66035 (15.6) | 20004 (5.1) | 29756 (3.8) |
| Dilated cardiomyopathy2 | 0.0 | 11213 (8.5) | 0.0 | 25905 (10.7) | 13653 (3.2) | 0 (0.0) | 0 (0.0) |
| Peripheral artery disease2 | 0.0 | 12548 (9.6) | 0.0 | 21898 (9.0) | 34585 (8.2) | 10077 (2.6) | 19203 (2.5) |
| Atrial fibrillation/flutter2 | 0.0 | 72003 (54.8) | 0.0 | 130554 (53.7) | 186715 (44.1) | 26067 (6.7) | 51643 (6.6) |
| Stroke2 | 0.0 | 20359 (15.5) | 0.0 | 35032 (14.4) | 70443 (16.6) | 33723 (8.7) | 77574 (9.9) |
| TIA2 | 0.0 | 4615 (3.5) | 0.0 | 8124 (3.3) | 15554 (3.7) | 8387 (2.2) | 17947 (2.3) |
| Stroke/TIA2 | 0.0 | 23199 (17.7) | 0.0 | 40138 (16.5) | 79974 (18.9) | 39439 (10.1) | 89746 (11.5) |
| Valvular disease2 | 0.0 | 27285 (20.8) | 0.0 | 49504 (20.4) | 64209 (15.2) | 7756 (2.0) | 13744 (1.8) |
| Renal failure2 | 0.0 | 20378 (15.5) | 0.0 | 34618 (14.2) | 45714 (10.8) | 6955 (1.8) | 11949 (1.5) |
| Dialysis2 | 0.0 | 1248 (1.0) | 0.0 | 2010 (0.8) | 4356 (1.0) | 638 (0.2) | 1052 (0.1) |
| Hyperkalemia2 | 0.0 | 2972 (2.3) | 0.0 | 5123 (2.1) | 4709 (1.1) | 602 (0.2) | 1053 (0.1) |
| Hypokalemia2 | 0.0 | 3921 (3.0) | 0.0 | 6421 (2.6) | 9887 (2.3) | 2081 (0.5) | 4185 (0.5) |
| COPD2 | 0.0 | 18139 (13.8) | 0.0 | 32305 (13.3) | 51046 (12.1) | 10677 (2.7) | 19834 (2.5) |
| Pneumonia/Flue/Respiratory infection2 | 0.0 | 47426 (36.1) | 0.0 | 84347 (34.7) | 151625 (35.8) | 36288 (9.3) | 72916 (9.3) |
| Liver disease2 | 0.0 | 3076 (2.3) | 0.0 | 5564 (2.3) | 7976 (1.9) | 2682 (0.7) | 4201 (0.5) |
| Obstructive sleep apnea2 | 0.0 | 5992 (4.6) | 0.0 | 11855 (4.9) | 10754 (2.5) | 5489 (1.4) | 7039 (0.9) |
| Dementia2 | 0.0 | 3217 (2.5) | 0.0 | 4128 (1.7) | 18786 (4.4) | 13965 (3.6) | 36473 (4.7) |
| Depression2 | 0.0 | 4901 (3.7) | 0.0 | 8669 (3.6) | 15516 (3.7) | 8932 (2.3) | 17272 (2.2) |
| Malignant cancer within 3 years2 | 0.0 | 17684 (13.5) | 0.0 | 31033 (12.8) | 54656 (12.9) | 43065 (11.1) | 79738 (10.2) |
| Muscoloskeletal/connective tissue diseases within 3 years2 | 0.0 | 42672 (32.5) | 0.0 | 77289 (31.8) | 124143 (29.3) | 77650 (20.0) | 137793 (17.6) |
| Alcohol abuse2 | 0.0 | 4304 (3.3) | 0.0 | 7896 (3.2) | 10905 (2.6) | 5620 (1.4) | 8426 (1.1) |
| Severe bleeding2 | 0.0 | 26017 (19.8) | 0.0 | 45062 (18.5) | 72078 (17.0) | 26954 (6.9) | 53037 (6.8) |
| Charlson Comorbidity Index2 | 0.0 | 3.0 [2.0, 4.0] | 0.0 | 3.0 [1.0, 4.0] | 2.0 [1.0, 4.0] | 0.0 [0.0, 2.0] | 0.0 [0.0, 2.0] |
| Charlson Comorbidity Index age-adjusted2 | 0.0 | 6.0 [5.0, 8.0] | 0.0 | 6.0 [4.0, 7.0] | 6.0 [5.0, 7.0] | 4.0 [2.0, 5.0] | 4.0 [3.0, 5.0] |
| Charlson Comorbidity Index2 | 0.0 | 0.0 | |||||
| 0-1 | 31969 (24.3) | 62378 (25.6) | 116632 (27.6) | 283820 (73.0) | 581741 (74.4) | ||
| 2-3 | 52454 (40.0) | 99073 (40.7) | 179391 (42.4) | 83214 (21.4) | 161696 (20.7) | ||
| 4-7 | 41110 (31.3) | 72399 (29.8) | 114013 (26.9) | 20289 (5.2) | 36410 (4.7) | ||
| ≥8 | 5763 (4.4) | 9363 (3.8) | 13056 (3.1) | 1518 (0.4) | 2555 (0.3) | ||
| Heart failure hospitalization2 | 0.0 | 35847 (27.3) | 0.0 | 88583 (36.4) | 154521 (36.5) | 0 (0.0) | 0 (0.0) |
| Number of heart failure hospitalizations2 | 0.0 | 0.0 [0.0, 1.0] | 0.0 | 0.0 [0.0, 1.0] | 0.0 [0.0, 1.0] | 0.0 [0.0, 0.0] | 0.0 [0.0, 0.0] |
| Any hospitalization2 | 0.0 | 90973 (69.3) | 0.0 | 180540 (74.2) | 336727 (79.6) | 233844 (60.1) | 528242 (67.5) |
| CV hospitalization2 | 0.0 | 59706 (45.5) | 0.0 | 129778 (53.4) | 239030 (56.5) | 80064 (20.6) | 190918 (24.4) |
| Non-CV hospitalization2 | 0.0 | 73691 (56.1) | 0.0 | 146058 (60.1) | 280667 (66.3) | 210453 (54.1) | 478550 (61.2) |
| Stroke/TIA hospitalization2 | 0.0 | 9772 (7.4) | 0.0 | 19129 (7.9) | 43120 (10.2) | 34197 (8.8) | 86779 (11.1) |
| Myocardial infarction hospitalization2 | 0.0 | 6670 (5.1) | 0.0 | 14237 (5.9) | 36231 (8.6) | 12763 (3.3) | 32840 (4.2) |
| Ischemic heart disease hospitalization2 | 0.0 | 11710 (8.9) | 0.0 | 27034 (11.1) | 58352 (13.8) | 18550 (4.8) | 45642 (5.8) |
| Ventricular fibrillation/tachycardia hospitalization2 | 0.0 | 1602 (1.2) | 0.0 | 4944 (2.0) | 5331 (1.3) | 280 (0.1) | 623 (0.1) |
| Pneumonia/Flue/Respiratory infection hospitalization2 | 0.0 | 22320 (17.0) | 0.0 | 45615 (18.8) | 96521 (22.8) | 36187 (9.3) | 88652 (11.3) |
| Pneumonia hospitalization2 | 0.0 | 14956 (11.4) | 0.0 | 30752 (12.6) | 63889 (15.1) | 27257 (7.0) | 66827 (8.5) |
| Acute renal failure hospitalization2 | 0.0 | 6401 (4.9) | 0.0 | 13716 (5.6) | 21857 (5.2) | 5097 (1.3) | 9450 (1.2) |
| End-stage renal failure2 | 0.0 | 2410 (1.8) | 0.0 | 5003 (2.1) | 9217 (2.2) | 1894 (0.5) | 3236 (0.4) |
| Malignant cancer hospitalization2 | 0.0 | 9373 (7.1) | 0.0 | 17382 (7.1) | 37916 (9.0) | 43452 (11.2) | 99197 (12.7) |
| Severe bleeding hospitalization2 | 0.0 | 18992 (14.5) | 0.0 | 38523 (15.8) | 71480 (16.9) | 39678 (10.2) | 91287 (11.7) |
| Hyperkalemia hospitalization2 | 0.0 | 813 (0.6) | 0.0 | 2039 (0.8) | 3114 (0.7) | 305 (0.1) | 618 (0.1) |
| Hypokalemia hospitalization2 | 0.0 | 413 (0.3) | 0.0 | 1015 (0.4) | 1578 (0.4) | 726 (0.2) | 1480 (0.2) |
| Syncope hospitalization2 | 0.0 | 3099 (2.4) | 0.0 | 7207 (3.0) | 13159 (3.1) | 7720 (2.0) | 19196 (2.5) |
| Trauma hospitalization2 | 0.0 | 17150 (13.1) | 0.0 | 33655 (13.8) | 72554 (17.1) | 53453 (13.7) | 145902 (18.6) |
| Coronary revascularization2 | 0.0 | 4212 (3.2) | 0.0 | 10582 (4.4) | 20177 (4.8) | 10766 (2.8) | 19832 (2.5) |
| Death2 | 0.0 | 75141 (57.2) | 0.0 | 131849 (54.2) | 326980 (77.3) | 148054 (38.1) | 443581 (56.7) |
| CV death2 | 0.0 | 43797 (33.4) | 0.0 | 78681 (32.4) | 190988 (45.1) | 45367 (11.7) | 155540 (19.9) |
| Non-CV death2 | 0.0 | 31344 (23.9) | 0.0 | 53168 (21.9) | 135992 (32.1) | 102687 (26.4) | 288041 (36.8) |
| Hospitalization or death Sudden cardiac death2 | 0.0 | 64 (0.0) | 0.0 | 118 (0.0) | 357 (0.1) | 113 (0.0) | 572 (0.1) |
| Composite CVD/HFH2 | 0.0 | 60779 (46.3) | 0.0 | 121798 (50.1) | 261346 (61.8) | 45367 (11.7) | 155540 (19.9) |
| Composite Death/HFH2 | 0.0 | 82530 (62.9) | 0.0 | 152709 (62.8) | 351416 (83.1) | 148054 (38.1) | 443581 (56.7) |
| Note: | |||||||
| Patients have different follow-up times, this means that outcomes can not be interpreted directly from the table. | |||||||
| Categorical variables are presented with n (%) and continuous variables with median [q1-q3]. | |||||||
| 1 Source: SwedeHF | |||||||
| 2 Source: NPR | |||||||
| 3 Source: SCB |
Statistics
Over time - interactive
Descriptive statistics over time can be found: https://swedehf.shinyapps.io/deskstatshfdb4